Eudora is a city in Douglas County, Kansas, United States, along the Kansas and Wakarusa rivers. As of the 2020 census, the population …Eudora is a city in Douglas County, Kansas, United States, along the Kansas and Wakarusa rivers. As of the 2020 census, the population of the city was 6,408. The Eudora area was home to various Native American tribes for thousands of years. The Kansa tribe lived in the Eudora area from the 1600s to the early 1800s. The Kansa lived along the rivers of this region in villages and practiced agriculture. A Kansa village was located at the site of modern day Eudora in the 1790s. In the 1820s the Kansa were forcibly removed from the region by the U.S. government to make room for the Shawnee tribe. The Oregon Trail and Santa Fe Trail passed through the region, just a few miles south of modern Eudora.