Marcola is an unincorporated community and census-designated place in Lane County, Oregon, United States, northeast of Springfield on the Mohawk River. The post office at this location was established in 1876 and originally called "Isabel" for early settler Isabel Applegate. In 1899-1900, a railroad was built through the Mohawk Valley and a station named M…Marcola is an unincorporated community and census-designated place in Lane County, Oregon, United States, northeast of Springfield on the Mohawk River. The post office at this location was established in 1876 and originally called "Isabel" for early settler Isabel Applegate. In 1899-1900, a railroad was built through the Mohawk Valley and a station named Marcola was established near the post office. Marcola was a name made up to honor Mary Cole, the wife of the town's founder, Columbus Cole. In 1901, the post office name was changed to agree with the name of the station.