Medscape2d
Angiotensin II-Receptor Antagonists: An Overview
Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...
Synthetic peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
SARS-CoV-2 invades host cells by binding to the ACE receptor on their surface via its spike protein (S). "The infection ...
Medscape12d
Renoprotective Effects of Adding Angiotensin II Receptor Blocker to Maximal Recommended Doses of ACE Inhibitor in Diabetic Nephropathy
by adding an angiotensin II receptor blocker (ARB) to treatment with maximal recommended doses of an ACE inhibitor (ACEI) in patients with type 2 diabetes and nephropathy. Research Design and ...
Nature5y
LCZ696, a novel dual inhibitor of neprilysin and the angiotensin II receptor, shows promise in phase II trial
The dual-action agent LCZ696 blocks the angiotensin II receptor (via a valsartan moiety ... neprilysin and angiotensin-converting enzyme (ACE), reduces blood pressure to a greater extent than ...
Nature5y
Do ACE inhibitors and ARBs have specific renoprotective effects?
In addition to their capacity to lower systemic blood pressure, angiotensin-converting-enzyme (ACE) inhibitors and angiotensin-II receptor blockers (ARBs) are thought to have specific ...