Spironolactone is a nonselective aldosterone antagonist, and eplerenone is selective to the aldosterone receptor. Although numerous clinical trials have evaluated the efficacy of each drug ...

and aldosterone-receptor antagonists, are administered either individually or collectively. Each of these drug classes reduces the homeostatic ability to eliminate ingested potassium loads by the ...

The effects of angiotensin include vasoconstriction and stimulation of aldosterone production. Inhibiting angiotensin receptors will decrease blood pressure through vasodilation and blockade of ...

Moreover, evidence suggests that adipocytes release secretagogues that stimulate aldosterone production independent of the renin–angiotensin system. Mineralocorticoid receptors are present in ...

CHICAGO -- A mineralocorticoid receptor antagonist (MRA ... Over 2 decades ago, the aldosterone antagonist eplerenone proved beneficial after MI complicated by left ventricular dysfunction ...

angiotensin receptor blockers, sacubitril/valsartan (Entresto, Novartis), continued beta-adrenergic blockade, aldosterone antagonists and HMG-CoA reductase inhibitors. Early antithrombotic ...