Disclosure: The author has been the recipient of research grant support from Pharmacia for participation in some of the research studies described herein and presented data from these studies at ...

Spironolactone is a nonselective aldosterone antagonist, and eplerenone is selective to the aldosterone receptor. Although numerous clinical trials have evaluated the efficacy of each drug ...

A rash is common with angiotensin receptor blockers. Hypotension can occur causing dizziness and weakness. Hyperkalemia can occur due to the aldosterone inhibition. Renal failure can occur due to ...

The finding that angiotensin II and aldosterone are proinflammatory ... inhibitors, angiotensin-receptor blockers (ARBs), mineralocorticoid-receptor antagonists, and direct renin inhibitors ...

The RAAS can be blocked by angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers, and aldosterone antagonists, as described in Treatment below. Both A-type (ANP ...

BioCity Biopharma’s selective endothelin receptor type A (ETA) antagonist has reduced excess ... 2 inhibitors and renin-angiotensin-aldosterone system inhibitors as background therapy.