Medscape2mon
Angiotensin II-Receptor Antagonists: An Overview
Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...
Medscape2mon
Angiotensin II Antagonists in the Treatment of Hypertension: More Similarities Than Differences
The question of whether there are real and clinically meaningful differences in antihypertensive efficacy within the AII antagonist class is potentially important for clinicians to optimize their ...
Nature10y
Design of angiotensin converting enzyme inhibitors
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu Angiotensin I Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Angiotensin II David W. Cushman In 1967, John Vane, a consultant at The Squibb Institute for Medical Research ...
Knowridge Science Report12d
Common blood pressure drug may increase suicide risk
A recent study has raised concerns about a possible link between a common type of blood pressure medication and an increased ...
Healthline29d
10 Common Blood Pressure Medication Classes
drowsiness or dizziness Angiotensin II receptor blockers These may be used to treat heart failure or after a heart attack. dizziness, headache, fatigue, and others Calcium channel blockers These ...
Monthly Prescribing Reference13y
Lisinopril/hydrochlorothiazide
Lisinopril, hydrochlorothiazide; 10mg/12.5mg, 20mg/12.5mg, 20mg/25mg; tabs. Lisinopril inhibits angiotensin-converting enzyme. It suppresses the renin-angiotensin-aldosterone system. The mechanism ...
Nature5y
LCZ696, a novel dual inhibitor of neprilysin and the angiotensin II receptor, shows promise in phase II trial
The dual-action agent LCZ696 blocks the angiotensin II receptor (via a valsartan moiety) and inhibits neprilysin (via an AHU377 moiety). In a phase II trial, this drug “demonstrated superior ...