Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...
Theoretically, the RAS may be interrupted at any of several points in the stepwise, enzyme-catalyzed synthesis of angiotensin II, and the action of the angiotensin II molecule, once synthesized ...
Its enzymatic activity was usually assayed by measuring the smooth-muscle-contracting activity of its product, angiotensin II, a laborious ... atoms that could also function as zinc ligands.
In addition to their capacity to lower systemic blood pressure, angiotensin-converting-enzyme (ACE) inhibitors and angiotensin-II receptor blockers (ARBs) are thought to have specific ...
Peptides have emerged as a focal point in molecular and biological research, providing a promising avenue for understanding ...