Angiotensin II (AngII), the major renin-angiotensin system ... we show that inhibition of the EGFR pathway prevents development of AngII-induced renal lesions. Furthermore, we provide evidence ...

In contrast, ARBs would be expected to inhibit the biologic effects of angiotensin II more completely than ACE inhibitors, since they block the pathway more distally at the level of the receptor ...

Angiotensin II acts directly on vascular smooth muscle ... But this route around the viscera is not the only pathway. “More and more it's getting recognized that a lot of these components ...