Alveolar Type 1 (AT1) Cells: Cells that form the majority of the surface area of the alveoli and are involved in gas exchange. Alveolar Type 2 (AT2) Cells: Cells that produce surfactant and can ...

Alveolar type 2 (AT2) cells maintain lung health by acting as stem cells and producing pulmonary surfactant. AT2 dysfunction underlies many lung diseases, including interstitial lung disease (ILD), in ...

"It's been recently discovered that the AT2 receptor is found in the lung's alveoli, the lung's air sacs, and it seems to be central to the proper functioning of the alveoli," explains Hallberg.

This cancer originates in the epithelial cells that line the lung’s alveoli, the tiny sacs responsible for gas exchange between the bloodstream and inhaled air. Most lung adenocarcinoma studies ...

It is a key mediator of extrusion therefore, to help validate whether extrusion is happening in alveolus an extrusion gene signature ... GSE135893; GSE128033). Cell types of focus included AT2, ...

FdAT2 organoids are an attractive genetic model for understanding fundamental mechanisms of AT2 cell biology in health, and modeling inherited disorders and environmental insults which perturb their ...