A new review highlights how gut microbiome imbalances contribute to cardiovascular disease by altering short-chain fatty ...
Carbohydrates are fermented by anaerobic colon flora to gas (CO 2, H 2, CH 4) and SCFA (acetate, propionate, and butyrate) in human adults. SCFA absorption is critical to normal colon function.
Butyrate, in particular ... showed similar chromatin accessibility effects in the study. The localization of SCFA-driven histone modifications further emphasizes their epigenetic importance.
The researchers found that both propionate and butyrate altered gene expression ... “Eating enough fiber increases SCFA production in the gut, which may help prevent colorectal cancer by ...