For instance, as previously mentioned, Rowley used G-banding patterns to determine that a translocation event involving chromosomes 9 and 22 was responsible for CML (Rowley, 1973). G-banding ...

People with the disorder might also have seizures, motor delays, small heads, short stature or low muscle mass, according to ...

Klinefelter syndrome is the most common sex chromosome disorder in men, affecting approximately one in 600 male births. The condition results from being born with an extra X chromosome ...

For instance, deletions that span a centromere result in an acentric chromosome that will most likely be lost during cell division. As with duplications, deletions can affect gene dosage and thus ...

In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes ... recessive disease or imprinting disorder. The detection rates vary between ...