Inspired by long-lived animals — and human centenarians — researchers are hunting for ways to enhance DNA repair and extend ...

Our DNA is under constant threat. Chemicals, radiation and the everyday errors of cell division all damage it, and if left ...

A new way for hard-to-treat cancer cells to protect themselves from being killed by anticancer drugs has been found. The ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

Cancer research, drug safety testing and aging biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage and ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Cancer cells rely on powerful genetic switches to keep growth genes running at full speed, but that intense activity can damage their own DNA. The resulting breaks are repeatedly repaired, sometimes ...

A clump of proteins seems to be in charge of the level of DNA repair that takes place in our bodies, determining how fast mutations accumulate in our cells over a lifetime – and might thus affect our ...

The longevity-linked APOE2 gene appears to protect brain cells by reducing DNA damage and helping neurons recover from stress. The finding could open a new path toward treatments that mimic APOE2’s ...

In a recent study published in the journal Nature, researchers found that the recruitment of neurons to memory circuits is preceded by a cascade of molecular events induced during learning, which ...

Each cell in our body experiences up to tens of thousands of DNA-damaging events per day, primarily from routine cellular maintenance or exposure to toxins in our environment. Despite the high ...