This diagram illustrates how the combination of fibroblast growth factor 4 and ascorbic acid activates the JAK2–STAT3 signaling pathway, promoting the maturation of induced cardiomyocytes (iCMs).

Their method relies on combining fibroblast growth factor 4 (FGF4 ... the JAK2–STAT3 signaling pathway. Through their research, the scientists employed advanced techniques like RNA sequencing ...

Interestingly, Boyle's research team also found that the 2GF-mediated increase in proinflammatory cytokine levels in fibroblast ... the PI3K pathway. “Targeting growth factor signaling may ...

An alternative signaling pathway, controlled by FGFR1 (fibroblast growth factor receptor 1), steps in and ensures growth and survival. "With the help of such 'bypasses', tumors react to external ...