Picks for every primetime game in Week 17
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The Lions need this game to have any playoff chance, but it won't be easy on the road. Minnesota has played outstanding defense. The problem is the Vikings have rookie Max Brosmer playing for the injured J.J. McCarthy. That could be an issue, even against a Lions defense that has struggled.
If Los Angeles pulls this off, it will have the hardest-won division title in recent memory. At 11-4, they can steal the AFC West from the Broncos by winning out, despite Denver rattling off 11 straight wins from Week 4 to Week 15. Unfortunately for the Chargers, they couldn’t be less equipped to face the two teams they have to beat.
Indianapolis, losers of six of the last seven, host the Jaguars in Week 17, who can win the AFC South with a win and a Houston loss, while the Colts would be eliminated with a loss or a Houston win among other outcomes.
With two weeks left in the 2025 NFL regular season, seven of the league's eight division titles are still up for grabs