Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

Visit NAP.edu/10766 to get more information about this book, to buy it in print, or to download it as a free PDF. With a growing human population and rising living standards, demand for animal-derived ...

Researchers have determined whether a specific chemical modification of a protein that packages the genome called a histone affects gene activity and cell proliferation. Researchers have determined ...

Discover how CRISPR genome editing is revolutionizing medicine. Learn the science of Cas9, current clinical trials, and the ...

A recent study led to the development of a powerful epigenetic editing technology. The system unlocks the ability to precisely program chromatin modifications at any specific position in the genome, ...

Mice and newts were applied to the one-step Cre-loxP organism creation technology by TAx9. In this study, the researchers succeeded in synthesizing a Cre-loxP integrated vector by placing a short DNA ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Researchers discover a protein that connects GLP-1 drugs to long-term, broad genomic responses that can promote pancreatic ...

Researchers demonstrated how Mycobacterium tuberculosis modifies its DNA and regulates both replication and gene activity through a reversible process known as ADP-ribosylation. This is the first time ...

Diet can leave lasting epigenetic marks that reshape gene expression, metabolic pathways, and disease susceptibility across the lifespan. These diet-driven molecular changes may create a form of ...