ING5 inhibits aerobic glycolysis of lung cancer cells: Study
Lung cancer, notorious for its high mortality rates, is a leading cause of cancer-related deaths globally, with metastasis ...
Nature4y
Cell Energy and Cell Functions
Glycolysis is an ancient, major ATP-producing pathway that occurs in almost all cells, eukaryotes and prokaryotes alike. This process, which is also known as fermentation, takes place in the ...
HIF1α identified as crucial for T cell activation in oxygen-poor tumors
Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their ...
EurekAlert!25d
Key regulator that induces cancer-killing capacity in T cells under hypoxia is identified
The UAB researchers found that HIF1α-glycolysis is indispensable for IFN ... “TILs and tumor cells utilize the same metabolic pathways for their growth and function, and co-live in the ...