Inflammatory signals via IL-6 through the JAK-STAT cascade induce the expression of the Hepcidin gene (HAMP). Higher EPO and HIF lead to the secretion of ERFE from erythroid precursor cells ...
Hepcidin, a peptide hormone secreted by the ... For example, injecting soluble HJV into mice results in inhibition of Hamp gene transcription and thereby increases iron acquisition and utilization ...
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