In 1999, Damier and colleagues identified two distinct sub-regions within the human substantia nigra using immunostaining against calbindin-D28K, a calcium-binding protein expressed in many ...

Substantia nigra. Illustration showing a healthy substantia nigra in a human brain. The substantia ... [+] nigra plays an important role in reward, addiction, and movement. Degeneration of this ...

Dopamine neurons in the substantia nigra and the ventral tegmental area are believed to be involved in reward-dependent behaviors. Consistent with this role, they are activated by rewards ...

Increased sodium and potassium ratios were observed in every region except the substantia nigra, and many of the regions showed ... after they died from the NZ Neurological Foundation Douglas Human ...