On the Eagles' end, their weakness has been turnovers. Philadelphia has four games this year with two or more turnovers and the Eagles have gone 0-4 in those games. If any defense out there can take advantage of that, it's a Bills unit that has forced 20 turnovers this year, which ranks in the top eight in the NFL.

This is probably one of the least interesting games of Week 16. The Saints are now 4-10 after playing spoiler the past two weeks against division rivals. The Jets, sitting at 3-11, still have a shot the top pick in the 2026 NFL Draft. Finally, I’ll be picking a home team to win. I’m going with New Orleans.

The Los Angeles Rams dropped a head-to-head matchup against the Seattle Seahawks but remained the Super Bowl favorites after Week 16's action. The Rams sit at +425, followed by the Seahawks at +550.

Having already beaten the Seahawks at home in Week 11, the Rams could have taken a major step toward securing their 16th NFC West title by sweeping the season series. However, the