A neural circuit hidden in an understudied region of the brain plays a critical role in turning temporary pain into pain that ...

New research suggests pain is not a simple signal of injury but a process that unfolds across nerves, spinal cord, and brain.

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

Chronic pain affects more than 50 million Americans, yet for decades, treatment options for pain that persists in the absence ...

Men and women experience pain differently, and until now, scientists didn’t know why. New research says it may be in part due to differences in male and female nerve cells. Pain-sensing nerve cells ...

New research discovers a link between estrogen and pain receptors in the colon, which may explain higher rates and intensity of irritable bowel syndrome-related symptoms in women.

Women of reproductive age are more likely than other people to report gut problems like irritable bowel syndrome (IBS), and can feel dismissed by doctors, as clinicians often put the pain down to diet ...

Around one million people every year suffer from a parasitic condition known as cutaneous leishmaniasis. Spread by sandfly bites, the parasite causes nasty skin ulcerations but for many people the ...

Adolescents who report pain at the age of 18 are at higher risk of later self-harm. This is shown by a new study from ...

The American College of Cardiology (ACC) expert decision pathway for chest pain can safely and effectively rule out acute coronary syndromes in most patients, but not for those with known coronary ...