The authors suggest that calreticulin acts as an essential recognition signal for phagocytosis ... the phagocyte about the imminent apoptotic death of the cell, ensuring efficient and rapid ...

This impairment leads to the accumulation of apoptotic cells, resulting in prolonged ... that enable microglia to accelerate the process of phagocytosis. Efferocytosis has emerged as a promising ...

With professional phagocytes nowhere to be seen, Stewart said, “The duty almost falls on the stem cells by default.” By knocking out RXRα in mice, she interfered with the ability of HFSCs, depicted in ...

CD14 mediates the recognition and phagocytosis of apoptotic cells through an unidentified ligand expressed by apoptotic but not by viable cells 15, whereas CD32 and CD64 mediate phagocytosis of ...

Although it was once thought that most programmed cell deaths occurred by the caspase-dependent program apoptosis, now numerous non-apoptotic programs have ... non-canonical autophagy called ...

Inefficient removal of dying cells results in human autoimmune and inflammatory diseases. On the other hand, targeted phagocytosis of cancer cells has recently been developed as a cancer treatment ...