Shown is the result of the reciprocal translocation of 22q to the lower arm of 9 and 9q (c-abl to a specific breakpoint cluster region [bcr] of chromosome 22 indicated by the arrows). Courtesy of ...

Less than a decade after Watson and Crick published their landmark paper on the structure of DNA, two Philadelphia researchers noticed that the blood cells of patients with chronic myelogenous ...

Specifically, the Philadelphia chromosome is a variant of chromosome 22 that is missing its long arm and, instead, has the long arm of chromosome 9. The transfer between the long arms of ...

Meanwhile, a New Drug Application (NDA) for another one of Ascentage Pharma’s key drug candidates, the novel Bcl-2 selective inhibitor lisaftoclax (APG-2575), has already been accepted and granted the ...