The compound inhibited the activation of signaling molecules associated with apoptosis, pyroptosis, and necroptosis, collectively referred to as PANoptosis. By regulating these pathways ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...

Ubiquitin-specific proteases play a critical role in regulating cell death pathways in breast cancer, affecting tumor ...

Researchers identified a Mtb effector protein, mammalian cell entry 3C (Mce3C), which promotes host cell necroptosis while inhibiting apoptosis. Mechanistically, Mtb Mce3C can bind host cathepsin ...