Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

Researchers show that loss of the SPRTN enzyme lets DNA–protein crosslinks accumulate, leak DNA into the cytoplasm, activate ...

A research team has identified a new mechanism that controls DNA’s ability to replicate—and thereby a cell’s ability to ...

UCSF scientists discover that the spindle, the structure that divides chromosomes equally during mitosis, actually gets stronger when it is stretched.

If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the ...

Every second, millions of cells in your body divide in two. In the space of an hour, they duplicate their DNA and grow a web ...

SAR11 bacteria dominate the world’s oceans by being incredibly efficient, shedding genes to survive in nutrient-poor waters.

DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that aid DNA in carrying out essential processes such as replication, repair, and ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

Chemists induced a cell-like behavior in molecular assemblies called vesicles. They used a sacrificial chemical fuel to make the vesicles divide into smaller versions of themselves. While this process ...