People with pockets of fat hidden inside their muscles are at a higher risk of dying or being hospitalized from a heart attack or heart failure, regardless of their ... Souza and colleagues ...

More information: Sadi Loai et al, Abnormal skeletal muscle and myocardial vasoreactivity manifests prior to heart failure in a diabetic cardiomyopathy rat model, Discover Medicine (2025).

Mutations in these proteins perturb their interactions with other proteins and their function, which leads to disease. Research in the Leinwand lab focuses on unraveling mechanisms of genetic heart ...

The myocardium is composed of a specialized type of muscle cell called cardiac muscle that is only found in the heart. Cardiac muscle is striated like skeletal muscle, but is controlled by both ...

In both affected siblings, an accumulation of amorphous material immunoreactive for desmin, dystrophin and vimentin was observed in the cytoplasm of the skeletal muscle cells. An uncle and the ...

Their technique opens the way for using implantation to treat unscarred muscle atrophied by aging. Age-related muscular atrophy in skeletal muscle can have a devastating impact on people's quality ...

Most DEGs exhibited a linear correlation with disease trajectory ... leading to dysregulated mTOR signaling, which causes skeletal muscle atrophy.

Age-related muscular atrophy in skeletal muscle can have a devastating impact on people's quality of life, as well as make them more susceptible to a wide range of diseases. Prevention regimens ...