These drugs treat numerous conditions that range from ulcerative colitis to eczema to arthritis ... Similarly, all members of the JAK enzyme family are known for their dual functionality.

When this microbial balance is disturbed, it can contribute to the development of chronic diseases like ulcerative colitis (UC), an inflammatory condition of the large intestine. For some patients ...

Ulcerative colitis primarily affects the colon and rectum ... Researchers at Johns Hopkins are currently studying an enzyme that may treat patients with inflammatory bowel disease, or IBD.