Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

Using advanced microscopy techniques and computational modeling, researchers have discovered how herpesvirus infection affects the host-cell nucleus. Researchers at the University of Jyväskylä ...

Scientists at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have discovered how a gene-regulating protein forms tiny liquid-like droplets inside the cell nucleus (the compartment ...

Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...

Cholesterol enhances melanoma cell invasion by making nuclei squishier, revealing a potential treatment target in cancer ...

Researchers at the University of Jyväskylä (Finland), in cooperation with national and international research groups, have shown that DNA viruses infect cells and take over the host cell nucleus, ...

In a recent landmark study, scientists have unveiled how HIV-1 penetrates the cell's nuclear barrier—a discovery that could reshape antiviral strategies. The research, led by Professor Peijun Zhang, ...

Herpes simplex virus partially liquefies the tightly packed, gel-like interior of human cell nuclei to copy itself faster, a new study shows. The research centers on how the nucleus of each human cell ...