In the earliest phase of creating human proteins, the protein complex NAC performs an essential task by starting the first ...

Animals such as spiders make fibers which are strong and elastic. These fibers have a polypeptide structure and serve as inspiration for research into the development of functional materials.

Recent advances in synthetic polypeptide and polymer chemistry have transformed the landscape of biomaterials by combining the precision of organic synthesis with the versatile functionalities of ...

Aza-peptides, peptide analogues in which one or more α-carbon atoms are replaced by nitrogen atoms, represent a promising class of compounds in therapeutic development. This structural modification ...

A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides. 1 This ...

How did catalytic organic polymers emerge on prebiotic Earth? Answering this essential question will unlock key understandings in the origin of life. A team of scientists at Tohoku University have ...

In nature, there are animals that make fibers that are strong and elastic—for example, the thread that spiders produce to make webs. These fibers have a polypeptide structure and serve as inspiration ...

By understanding how milligram to kilogram peptide production is achieved safely, drug developers can better navigate the ...

Fibrous structures act as load-bearing components in vivo in many natural proteins besides enzymes, which are soluble globular molecules. Natural evolutionary processes have produced structural ...

Discover how therapeutic peptides act as biological messengers to treat disease, improve metabolism, and enhance immune ...