Objectives Systematic reviews and meta-analyses are the foundation of modern evidence-based medicine and their use is becoming more prolific than randomised trials. However, systematic reviews are ...

Objective To estimate associations between trivalent influenza vaccination and COVID-19 mortality as well as severe clinical outcomes among hospitalised patients. Design Retrospective observational ...

2 Center for Evidence-based Medicine & Health Outcome Research, University of South Florida & H Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA ...

Introduction There is growing interest in applying shared decision making approaches to support informed consent, a vital but challenging aspect of conducting clinical research. We systematically ...

Objectives Bronchiolitis is the commonest reason for hospital admission in infants in the first year of life. 1 Bronchiolitis, a viral chest infection, is a clinical diagnosis with no effective ...

New government legislation is necessary to ensure full transparency of industry payments in the UK’s healthcare. A first step ...

Background Health technology assessment (HTA) is a valuable tool for informing the efficient allocation of resources in healthcare. However, the resource-intensive nature of HTA can limit its ...

Objectives To assess whether the gender (primary) and geographical affiliation (post-hoc) of the first and/or last authors are associated with publication decisions after peer review. Design ...

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Drug treatment to reduce cholesterol to new target levels is now recommended in four moderate- to high-risk patient populations: patients who have already sustained a cardiovascular event, adult ...

1 Department of Internal Medicine and Clinical Epidemiology, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia 2 Centre for Academic Research in Geriatric Medicine ...