In summary, extensive data support that titin’s passive force augments actomyosin interaction. At low passive force (short SLs), interactions between myosin heads and the A-band segment of titin may ...
Request permissions for this article. This study was supported by the National Heart, Lung, and Blood Institute grant R35HL144998 (to H. L. Granzier) and the Leducq Foundation (grant 13CVD04 to H. L.