The discovery and development of GLP-1 receptor agonists for type 2 diabetes and obesity is a bench-to-bedside success story.1 Multiple GLP-1 receptor agonists are now in clinical use, such as ...

Université de Bourgogne, U1231 INSERM, CTM, Equipe DesCarTes, UFR Sciences de Santé, 7 Bd Jeanne d’Arc, 21078 Dijon Cedex, France ...

Furthermore, microglia influence iron-related signaling pathways, particularly through the TLR4 mediated ... which is converted into the effector molecule angiotensin-II upon binding to AT1 receptors ...

Hope is not passive wishing but an active, dynamic process. According to Hope Theory, hope involves two components: agency and pathways. Agency is the belief in one’s capability to act ...

Bahrain’s Bank ABC has mandated joint lead managers and book runners for perpetual Additional Tier 1 capital securities to be listed on London Stock Exchange (LSE) The bank has mandated Bank ABC, ...

State Key Laboratory of Pollution Control and Resource Reuse, School of Environment, Nanjing University, Nanjing 210023, P. R. China ...

In the legal battle over the write-down of AT1 bonds before a New York court, U.S. lawyers are ramping up their efforts, putting Switzerland under mounting pressure. The acquisition of Credit Suisse ...

AIB said the "Additional Tier 1" (AT1) perpetual bond further supports the lender in meeting its regulatory capital requirements. It also marks the first Euro AT1 deal of the year in Europe ...

Sacubitril/valsartan inhibits neprilysin (NEP) and the binding of Ang II to its receptor AT1R; thereby preventing the activation of intracellular signaling cascades. Consequently, there is a reduction ...

Summer scholarship applications are now available in the Go System. Refer to "Funding Your Pathway Experience" below for more information. Finding Your Pathway Experience Schedule an individual ...