Annie (Kristen Wiig), is a maid of honor whose life unravels as she leads her best friend Lillian (Maya Rudolph) and a group of colorful bridesmaids (Rose Byrne, Melissa McCarthy, Wendi McLendon ...

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Four very different women, best friends during high school many years earlier, gather in the small town where they grew up for a reunion as bridesmaids in preparation for a wedding for a fifth friend.