We generated a new type of MHC multimers, which can be monomerized in the presence of a competitor, resulting in rapid loss of the staining reagent. Following dissociation, the T cells are ...

Brain cells receive sensory inputs from the outside world and send signals throughout the body telling organs and muscles ...

The short answer is a resounding — yes, and it really isn't that much work. If you're seriously considering staining your concrete, you may think the benefits far outweigh the disadvantages, but these ...

Significance: We extend the capabilities of virtual staining from AF to a different disease and stain modality. Our work includes newly developed virtual stains for H&E and a multiplex ...

3.5 Multiple immunofluorescence stain of tissue samples from ESCC patients To validate the accuracy of the analytical results in tumor tissues from ESCC patients, we selected for mIF staining, based ...

1092490500) and rinse. For immunofluorescence, the procedure was similar, but sections were incubated in fluorochrome labeled secondary antibody, followed by blocking and rinse. The staining ...

T cell infiltration by cCAS/STING-dependent CXCL10 secretion is associated with IFNγ secretion by CD8 + T cells, ultimately resulting in PD-L1 upregulation on tumour cells. On the contrary, ...

Anti-CD109 addition did not reduce the TNF-α-induced or IL-1β-induced increase in IL-6, MMP-3, CXCL9 and CXCL10 levels in CD109 KO FLSs, as it did in WT FLSs (online supplementary figure 4A-D). These ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Histone deacetylase HDAC6 has been implicated ...

In vitro and in vivo assays, including flow cytometry, immunofluorescence, Seahorse assay, and tumor xenograft models, were carried out to validate our findings. A total of 83,622 cells were enrolled ...