Glaucoma is a complex and multifactorial neurodegenerative disorder primarily characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual ...

Dysregulation of the Wnt pathway, with constitutive activation of beta catenin-driven oncogenic transcription, is a shared root cause of uncontrolled cell proliferation across multiple types of ...

Sanofi’s Sarclisa has been approved by the European Union as the first anti-CD38 therapy in combination with VRd to treat adult patients with n ...

DPTX3496 is an oral, small molecule condensate modulator (c-mod) targeting beta catenin to address Wnt-driven colorectal cancer (CRC), triple-negative breast cancer (TNBC), and non-small cell lung ...

epithelial cell dysfunction and death, pulmonary oedema, hyaline membrane formation and hypoxia. Neutrophil migration into sites of inflammation is a highly regulated and complex process that is ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed.

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.