Researchers showed that in C. elegans, the protein MBD-2 regulates genes through repressive histone marks rather than DNA ...

Epigenetic modifications such as DNA methylation play a key role in regulating gene expression. Emerging evidence suggests ...

Researchers at the School of Biological Sciences of The University of Hong Kong (HKU) have uncovered how eukaryotic cells can ...

This study addresses endosomal escape in oligonucleotide therapies and how engineered peptides can enhance intracellular drug delivery efficiency.

Epigenetic modifications such as DNA methylation play a key role in regulating gene expression. Emerging evidence suggests that intermediates ...

Figure 1. Dual binding patterns of MBD proteins in mammals and in C. elegans.In mammals (left), previous studies show that most MBD3 binding sites ...

Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...

Deep-learning model decodes the regulatory effects of DNA changes ...

Google DeepMind released AlphaGenome on January 28, an AI model that predicts how DNA sequences translate into biological functions, processing up to one million base-pairs at once and outperforming ...

Interpretation is the discipline through which molecular datasets reveal their significance. As the life sciences enter a new era defined by data richness and technological capacity, interpretive ...

City St. George’s researchers identified 9 genetic signatures and epigenetic changes driving lapatinib resistance in HER2-positive breast cancer. Cancer scientists from City St George’s, University of ...