A study by DKFZ researchers shows that inhibiting the enzyme aldolase A in glycolysis traps energy in liver cancer cells, ...

Glycolysis is an important sugar degradation pathway that cancer cells in particular depend on. Scientists at the German Cancer Research Center (DKFZ) have now shown that liver cancer cells in mice ...

In a groundbreaking study led by Dr. Ying Chen and her team from Ruijin Hospital, Shanghai Jiao Tong University School of ...

Yale researchers are sifting through a mosaic of cells in a living animal—both normal cells and mutated cells—to better ...

newly formed Biocell Energetics offers a suite of assays to monitor energy flux within cells’ mitochondria as well as the energy emanating from glycolytic pathways. Drug developers can use these ...

Results We observed that MSU and CPP crystals led to a metabolic rewiring toward the aerobic glycolysis pathway explained by an increase in GLUT1 plasma membrane expression and glucose uptake on ...

LIN treatment decreased the expression of muscle RING-finger protein-1 (MuRF1) and Atrogin1(MAFbx) in muscle, and the activation of insulin-like growth factor-1 (IGF-1)/protein kinase B (Akt)/forkhead ...

In recognising this UK Sport’s approach to funding reflects that journey and works on the basis of an athlete pathway with three clear and distinct levels that make up the World Class Pathway. The two ...

In summary, our findings indicate that the TIPE/PKM2/HIF-1α signaling pathway plays a pivotal role in promoting cancer stem cell properties by facilitating the glycolysis, which would provide a ...