I still vividly remember the first time we observed neurons responding not to audible sound, but to concentrated, precisely ...

Using an aging clock, researchers from the University of Cologne have used the Caenorhabditis elegans model organism to demonstrate that nerve cells age differently. They identified both the causes of ...

Parkinson’s disease has long been defined by the slow, relentless loss of dopamine-producing neurons, with treatments focused ...

Scientists discovered why some neurons resist tau toxicity, identifying CRL5SOCS4 as a crucial defense and linking ...

Findings revealed biological pathways as potential intervention points, and demonstrated in fruit flies potential therapeutic strategies.

Key takeawaysTau is the most common protein that aggregates in neurodegeneration diseases. However, researchers had not ...

Brain tissue analysis shows reactive microglia in Parkinson’s disease overexpress Fc gamma receptors, which may lead to inappropriate elimination of functional dopaminergic neurons. These findings ...

Researchers found that cutting the vagus nerve in mice reduced dopamine activity and lessened the frequency of reward ...

Amyloids are typically associated with neurodegenerative diseases such as Alzheimer's, Huntington's and Parkinsons. They form tightly packed, highly stable "detrimental" protein fibers that destroy ...

Using an aging clock, researchers from the University of Cologne have used the Caenorhabditis elegans model organism to demonstrate that nerve cells age differently. They identified both the causes of ...

Cells shrink a major internal structure as they age. New research shows this downsizing is deliberate—and linked to longer ...

As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why. It is increasingly clear, though, that the loss of synapses-the flexible and adaptive relay ...