Mount Sinai and BPGbio scientists uncover novel molecular drivers from live brain samples that direct human brain structure and function from ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...

RAB7A plays a central role in the final stages of autophagy, facilitating autophagosome-lysosome fusion, lysosome positioning, and cargo degradation. Its activation by guanine nucleotide exchange ...

Our body’s “blood factory” consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this ...

Researchers at the Icahn School of Medicine at Mount Sinai have characterized how cellular senescence—a biological process in which aging cells change ...