Could viral infections play a role in Huntington's disease? Research suggests Apolipoprotein B mRNA editing catalytic ...

APOBEC enzymes, which normally help fight viral infections by mutating viral DNA, cause repeat expansions and are unusually ...

New genetic research shows why some people develop deadly Huntington's disease earlier than others. The findings could lead ...

Researchers have made a major breakthrough in our understanding of Huntington's disease. This genetic disorder has long been ...

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time.

A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over ...

Researchers at Tufts University revealed a possible molecular mechanism explaining how the DNA repeats are broken and then expanded in the Huntington’s disease gene, pointing to a component of the ...

People genetically susceptible to Huntington's disease often see their movement, mood, and cognition decline slowly over time ...

Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though ...

Studies of living participants and postmortem brains confirm that gene expansion is a promising target for HD prevention ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death.

By Dr. Sanchari Sinha Dutta, Ph.D. Study uncovers how gradual CAG repeat expansion in neurons drives the onset of ...