Through cytokine screening, we identified that interleukin-1β (IL-1β), a key mediator of inflammation, inhibits syncytia formation mediated by various SARS-CoV-2 strains. Mechanistically, IL-1β ...

Second, they investigated the IL-1 signaling pathway in detail, using knockouts or pharmacological perturbation to understand the signaling proteins responsible for blocking cell fusion. They found ...

Recent developments in the field include an evolving treatment landscape and the development of evidence-based guidelines.

The FDA granted approval to Eli Lilly and Company’s mirikizumab-mrkz (Omvoh) for Crohn disease, expanding its treatment reach ...

In disease, high levels of IL-1 in the brain are linked to neuroinflammation, which can disrupt the body's stress response, ...

Lilly has also submitted marketing applications for Mirikizumab-mrkz in Crohn’s disease around the globe, including in the ...

Shares of Coherus BioSciences rose 4.5% to $1.8 in pre-market activity after it released positive med-stage results for its ...

AbbVie and Neomorph are forming a partnership and option-to-license agreement to develop molecular glue degraders, aiming to ...

Coherus BioSciences (CHRS) announced final data from its Phase 2 open label clinical trial evaluating casdozokitug, a selective and potent ...

A study found patients treated with interleukin inhibitors did not experience a difference in the rates of major adverse ...

One reason is the fact that much research related to ovarian cancer has focused on strategies combining chemotherapy with ...

A study shows a chain: low emotional clarity is linked to depression, and this clarity is influenced by higher inflammation ...