and it will also work on a metabotropic glutamate receptor subtype 7 negative allosteric modulator (NAM). Both are in preclinical development. Other companies working on PAMs include Cerevel ...
Increasing gamma-aminobutyric acid (GABA) and balancing glutamate, brain chemicals called neurotransmitters ... levels to rise but instead increase activity by stimulating receptors. GABA agonists ...