They are formed in a woman's body before birth and have to be on standby for decades to possibly be fertilized one day. But as they age, they accumulate more and more DNA damage. Until now, it has ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Here they establish an O-glycoproteome map of the mouse testis, providing insights ... for meiosis initiation and male fertility. Chromosome synapsis is an essential process during meiotic ...

The second act of a popular reprogramming factor could maximize the potential of iPSCs in research and regenerative medicine.

The highest LOD score for each combination of chromosomes ... The M16 mouse: an outbred animal model of early onset polygenic obesity and diabesity. Obes. Res. 12, 1397–1407. Allan, M. F., Eisen, E. J ...

It is a detailed view of the brain like never seen before. In a significant technological leap, University of Florida ...

A new AI tool builds sophisticated map of mouse brains. It is a detailed view of the brain like never seen before. In a significant technological leap, University of Florida researchers have created a ...

The first complete DNA methylation atlas of 39 human cell types reveals which genes can talk or are silenced, depending on whether their sequence is linked to methyl group epigenetic modification that ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

In a new study published in Developmental Cell, researchers led by Université de Montréal (UdeM) professor Greg FitzHarris show how the early mouse embryo ... number of chromosomes in cells ...