Intracellular staining was then performed with antibodies specific for ... supplemented with 10% fetal bovine serum and 5 ng/mL FGF-2 (R&D Systems). Migration of neutrophils, isolated from PBMC of HDs ...

This study describes a valuable new model for in vivo manipulation of microglia, exploring how mutations in the Adar1 gene within microglia contribute to Aicardi-Goutières Syndome. The methodology is ...

During islet development, beta-cell death, rather than proliferation alone, regulates beta-cell mass and shapes the immune ...

Acute respiratory distress syndrome (ARDS) is a neutrophil-dominant disorder with no effective pharmacological therapies. While the cyclin-dependent kinase inhibitor AT7519 induces neutrophil ...

1 Institute of Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Mainz, Germany 2 Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany ...

This condition commonly causes monocytopenia, and it can cause neutropenia (low neutrophils) or aplastic anemia (lack of blood cell production) as well. The effects can begin as early as infancy or as ...

We describe a rare case of serositis complicating permanent pacemaker implantation presenting 4 weeks postinsertion. A high index of suspicion for this potentially fatal complication is warranted to ...