BACKGROUND: The disruption of the blood–brain barrier (BBB) is a central pathogenic event in many central nervous system disorders. However, the mechanisms regulating BBB function remain incompletely ...

An intersection near HSHS St. John's Hospital in Springfield is expected to be closed at least a day after a water main break ...

Police are investigating a death in Springfield on Wednesday, Feb. 4. Cris Swaters, public affairs officer for SPD, tells ...

President Donald Trump demanded a swift end the partial government shutdown as debate intensifies over ICE and the administration’s immigration enforcement.

The bill filed in the Missouri Legislature, would take away citizens' rights to a referendum petition in rezoning cases.

Springfield has been in the national spotlight since 2024, when Vance and Trump made false claims about pets being eaten.

Tenants who live at the Kimball Towers Condominiums in Downtown Springfield have called our newsroom with complaints; some ...

The City of Springfield kicked off Black History Month with its 40th annual Black American Heritage Flag Raising ceremony at ...

What is Temporary Protected Status and how will potential ICE activity affect Springfield, Ohio? Learn more in this FAQ from ...

As Republican leadership in the House hopes to begin the process of reopening the government by advancing a funding package ...

Buried in large, underground salt caverns along Texas and Louisiana’s coast, the world’s largest supply of emergency crude ...

Carr was the only player on either team in double figures with 13 points, and he added seven rebounds. He’s the latest in a ...