Membrane proteins are vital for cellular signaling, transport, and communication, making them attractive drug targets despite their challenging properties. Advances in mass spectrometry have enabled ...
HER2 and ABCC1 are identified as significant transcriptomic predictors of overall survival in patients treated with T-DXd. A large-scale analysis reveals novel predictors of survival and resistance ...
Researchers have revealed how patients with metastatic breast cancer develop resistance to Enhertu treatment.
The study analyzed 2,799 T–DXd–treated breast cancer patients and found that WTS identified ERBB2 (HER2) and ABCC1 as the strongest transcriptomic predictors of T–DXd–specific overall survival. Higher ...
FAYETTEVILLE, GA, UNITED STATES, January 15, 2026 /EINPresswire.com/ -- Understanding why cancer cells rely on specific ...
Kazia Therapeutics , an oncology-focused pharmaceutical company developing novel therapies for difficult-to-treat cancers, ...
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Study identifies Apex1 as a redox-regulated driver of fracture repair
Bone fractures usually heal efficiently, but in some patients this process fails, causing nonunion. A recent study identifies ...
Acute exercise triggers circulating changes that improve DNA damage repair and remodel gene expression in colon cancer cells, ...
Cells operate on rules not vibes, including when on the precipice of persisting or perishing. Yet, with prior research ...
Bone fractures usually heal efficiently, but in some patients this process fails, causing nonunion. A recent study identifies ...
Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and ...
Colorectal cancer is one of the most prevalent tumors and a leading cause of cancer-related mortality. Despite advances achieved in recent years, resistance to available treatments remains one of the ...
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