AutoDock is a suite of automated docking ... site. LUDI. LUDI, another module in Discovery Studio, constructs possible new ligands for a given protein of known three-dimensional structure.

In chemotaxis, the aspartate receptor becomes an inhibitor of the kinase cascade. The aspartate receptor is also induced into becoming a better substrate for methyltransferase, thereby allowing ...

A Louisiana mall was the site of an apparent false alarm about an active shooter just two days after the carnage in New Orleans. A Lafayette Police spokesman confirmed to the Acadiana Advocate ...

Methods: The possible inhibitors of TRIB3 were screened by high-throughput molecular docking, CETSA, and CO-IP assay ... was used for immunoprecipitation. Protein A/G agarose beads (catalog number ...

After ligand binding, the receptor associated JAKs become active ... kinase kinase kinases (MAPKKK, MKKK, or MEKK), a family of proteins of which the c-Raf proto-oncogene is the most prominent member.

Helmholtz Institute for Pharmaceutical Research (HIPS)−Helmholtz Centre for Infection Research (HZI), Saar-land University, Campus E8.1, 66123Saarbrücken, Germany Department of Pharmacy, Saarland ...

In this study, we identify an E3 ubiquitin ligase, tripartite motif-containing protein 32 (TRIM32), as a key regulator ... sensitivity and reverses fatty liver Altered INSR levels and kinase activity ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. This study aimed to develop curcumin-loaded maltodextrin-based ...

Despite their significance, the precise mechanisms that govern protein acylation and deacylation remain largely elusive. Recent studies have made strides in this area by identifying novel ...