Key findings A collaborative team including Emeritus Professor Tei H. (Kanazawa University), Associate Professor Takahata Y. ...

In a simulated jet lag mouse model (6-hour light-dark phase advance), a single oral dose of Mic-628 shortened re-entrainment ...

Crystal structures of the Lac repressor, with and without isopropylthiogalactoside (IPTG), and the repressor bound to operator have provided a model for how the binding of the inducer reduces the ...

A Japanese research team has discovered a new compound that can advance the body's internal clock—offering hope for faster ...

We have determined the solution structure of the complex between the 'winged-helix' enhancer binding domain of the Mu repressor protein and its cognate DNA site. The structure reveals an unusual use ...

A Japanese research team has discovered a new compound that can advance the body’s internal clock—offering hope for faster recovery from jet lag and ...

Scribe expects to initiate a first-in-human hypercholesterolemia study in mid-2026 with STX-1150, its lead cardiometabolic assetSTX-1150 is designed to deliver durable therapeutic LDL-C lowering with ...

A Japanese research team has discovered a new compound that can advance the body's internal clock—offering hope for faster recovery from jet lag and better adaptation to night-shift work. The compound ...

The company, founded by UC Berkeley scientists including Jennifer Doudna, is preparing to test its lead candidate STX-1150 in ...