Safer and more broadly effective rotavirus vaccines could be achieved if initial investigations 1 into the boosting effect of plant-derived virus-like particles hold up in further trials.

The resulting chimeric P particles also maintained the major ... P particle–VP8* chimera as a promising dual vaccine against rotavirus and NoV and the P particle–M2e chimera against influenza ...

Risk of Transmission of Vaccine-Strain Rotavirus in a Neonatal Intensive Care Unit That Routinely Vaccinates. Pediatrics , 2024; DOI: 10.1542/peds.2024-067621 Cite This Page : ...

Researchers from Children's Hospital of Philadelphia (CHOP) found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences ...

Our studies using monoclonal antibodies, reassortants, and baculovirus-expressed virus-like particles have provided insights into the molecular mechanisms of cell entry, infectivity, transcription, ...

The rotavirus shares some structural similarities ... "It doesn't take many virus particles to make you sick," lead researcher Richard Quilliam told The Telegraph. "And if the viruses then release ...

The resulting chimeric P particles also maintained the major antigenic epitopes of the P particles, allowing the production of dual vaccine against NoV and the inserted antigens to be developed.