The 49ers take on the Seahawks and face an uphill battle according to latest odds. Here is what the predictions have to say: ...

USA Today's NFL experts make their picks for an NFL playoff showdown between the Seattle Seahawks and San Francisco 49ers ...

The San Francisco 49ers have already lost defensive coordinator Robert Saleh to the Tennessee Titans. Now, Saleh is ...

San Francisco 49ers general manager John Lynch suggested WR Brandon Aiyuk's time with the team is done in a Jan. 21 press ...

San Francisco 49ers are one of the most injured teams in the NFL. Conspiracy theorists have developed a theory as to why that is, but is it true?

The Seattle Seahawks host the San Francisco 49ers in the second game of the NFL divisional playoffs. Here's how to watch.

The San Francisco 49ers will face off against the Seattle Seahawks in the NFC divisional round Saturday. Here is how to watch.

The 49ers will be a wild-card in the NFC after losing to the Seahawks in Week 18. Here's what to know about their wild-card ...

USA Today's NFL experts make their picks for an NFL playoff showdown between the Philadelphia Eagles and San Francisco 49ers ...

San Francisco 49ers general manager John Lynch said Brandon Aiyuk has likely "played his last snap" for the team. Check out ...

The 49ers beat the Bears in a tightly contested shootout on 'Sunday Night Football' in Week 17. Here are the highlights and ...