Frontiers12d
Accurate identification of snoRNA targets using variational graph autoencoder to advance the redevelopment of traditional medicines
Dysregulation of snoRNA in vivo can lead to tumorigenesis ... SNORD33, typically located in the nucleolus, primarily facilitates the chemical modification of rRNA, such as guiding rRNA methylation ...
eLife18d
SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis
Overall, these findings indicate a rather fluid role for SERBP1 in translation regulation, promoting or repressing different translational steps and acting in rRNA processing/modification and ribosome ...
SciTech Daily25d
Scientists Discover “Mortality Timer” Inside Our Cells
Cornell researchers found that smaller nucleoli in cells could slow aging and extend lifespan, a principle evident in yeast but applicable to humans, offering a potential pathway for new longevity ...
eLife1mon
Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA
This important study by Bi and colleagues employed a clever genetics screen to uncover the role of the GidB rRNA methylase in translation fidelity, under certain conditions, in Mycobacterium smegmatis ...
Frontiers4y
Low Turnover of Soil Bacterial rRNA at Low Temperatures
Ribosomal RNA (rRNA) is used widely to investigate potentially active microorganisms in environmental samples, including soil microorganisms and other microbial communities that are subjected to ...